Versus Arthritis Centre for Sport, Exercise and Osteoarthritis
University of Nottingham

The MILOs Consortium: Meta-analysis of International Lower-limb Osteoarthritis Cohorts

What this research hopes to achieve

  1. To quantify the association between physical activity and incident hip or knee osteoarthritis in the normal population in an individual patient data meta-analysis
  2. To assess the risk of premature mortality in subjects with lower-limb osteoarthritis in an individual patient data meta-analysis
  3. To establish collaborative links with other international cohorts in order to develop osteoarthritis-based research questions with increased generalizability across subjects from different countries and races
  4. To establish the methodology for harmonising physical activity risk factors and osteoarthritis outcomes between prospective population-based cohort studies
Work Package  Epidemiology (WP1
Principal Investigator  Prof Nigel Arden (Oxford) 
Investigators  Dr Kirsten Leyland and Dr Lucy Gates