Prediction of stress fracture during Royal Marine recruit training: Surgeon General's bone health project
Background
Hip Osteoarthritis (OA) is one of the most common joint diseases and one of the major causes of disability, especially in adults and in high income countries. In the United Kingdom (UK) in 2011 more than 60,000 total hip replacements were carried out due to OA. To reduce the need for these operations, we need to find out who is more likely to develop hip OA. If these high risk people can be found, health service plans to reduce this public health problem can be developed.
Several risk factors of hip OA have been found, including old age, being female, high body mass index, high physical workload, high frequency of physical activities, long-term oestrogen replacement therapy (ERT) use, loss of cartilage and joint deterioration. However, it is unclear which of these combined factors contributes most to the development of hip OA.
What the research hopes to achieve
The aim of this project is to identify which risk factors are associated with radiographic hip OA over a 6 year period. We will use data from the Chingford Women’s Study. This was initiated in June 1989 with 1003 females aged 44 years or older living in Chingford (London, UK) to look at the health of women in mid-life.
| Work Packages |
Epidemiology (WP1) |
| Principal Investigator |
Prof Nigel Arden (University of Oxford) |
| Investigators |
Dr Maria Sanchez and Dr Kirsten Leyland |
| Collaborators |
Chingford Women's Study population and King's College London |