Versus Arthritis Centre for Sport, Exercise and Osteoarthritis
University of Nottingham

Centre Publications - 2014

See below for a list of the Centre's publications, oral presentations, posters and reports during 2014. 

Click on the Quick links to view publications from other years.


Adams, j., and lempp, h., (2014) patient involvement in research: what is the evidence and the scope of patient and public involvement in musculoskeletal research? Rheumatology, 53, (s1), p.i7

Adams, j., barbosa boucas, s., hislop, k., dziedzic, k., arden, n., graham, c., mckenna, h., jansen, v., shaylor, b., macleod, c., bancroft, k., bradley, s. (2014) the effectiveness and efficacy of splints for thumb base osteoarthritis: a pilot randomised controlled trial. Rheumatology, 53, (s1), p.i41.

Agyapong-badu, s, warner, m, samuel, d, narici, m, cooper, c, stokes, m anterior thigh composition measured using ultrasound imaging to quantify relative thickness of muscle and non-contractile tissue: a potential biomarker for musculoskeletal health. Institute of physics and engineering in medicine. Physiol meas. 35 (2014) 2165-2176

Barnes n, agyapong-badu s, walsh b, stokes m, samuel d. Reliability and acceptability of measuring sniff nasal inspiratory pressure (snip) and peak inspiratory flow (pif) to assess respiratory muscle strength in older adults: a preliminary study. Aging clinical and experimental research 2014; 26(2):171-176.  Doi:10.1007/s40520-013-0146-2

Bergmann g., bender a., graichen f., dymke j., rohlmann a., trepczynski a., heller m.o., kutzner i. Standardized loads acting in knee implants.plos one [2014]; 9(1): e86035

Botha N, Warner M, Gimpel M, Mottram S, Comerford M, Stokes M. Movement patterns during a small knee bend test in academy footballers with femoroacetabular impingement (FAI).  Working papers in the health sciences 2014; 1:10 winter

G. Musumeci, p. Castrogiovanni, f. M. Trovato, r. Imbesi, s. Giunta, m. A. Szychlinska, c. Loreto, s. Castorina, a. Mobasheri. Mild physical activity ameliorates cartilage degeneration in a rat model of ageing: a study on lubricin expression. Scandinavian journal of medicine and science in sports (june 2014)

Gay a, culliford d, leyland k, arden nk and bowen cj. Associations between body mass index and foot joint pain in middle-aged and older women: a longitudinal population-based cohort study. Arthritis care and research. Epub ahead of print. Doi: 10.1002/acr.22408

Giunta s, castorina a, marzagalli r, szychlinska ma, pichler k, mobasheri a and musumeci g. Ameliorative effects of pacap against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis.  Internationa journal molecular science (2015) 16, 5922-5944 doi: 10.3390/ijms16035922

Glyn-jones s, palmer aj, vincent t, price aj, wienans h, carr aj, advances in the treatment of osteoarthritis. The lancet 2015 jul 25;386(9991):376-87. Doi: 10.1016/s0140-6736(14)60802-3.

Haddad b, konan s, haddad fs. Debridement versus re-attachment of acetabular labral tears: a review of the literature and quantitative analysis. Bone joint j. 2014 jan;96-b (1):24-30

Halstead-rastrick j, keenan am, mcgonagle d. Conaghan pg, redmond ac. An exploration into the effect of foot orthoses on bone marrow lesions associated with mechanical foot pain. Journal of foot and ankle research 2014, 7(suppl 2): a1

Hardcastle sa, dieppe p, gregson cl, arden nk, spector td, hart dj, edwards mh, dennison em, cooper c, williams m, davey-smith g, tobias jh. Osteophytes, enthesophytes and high bone mass; a bone-forming triad with relevance for osteoarthritis? Arthritis rheumatol. 2014 jun 6. Doi: 10.1002/art.38729. [epub ahead of print] pubmed pmid: 24910132.

Henrotin y, marty m, mobasheri a.  Maturitas. 2014 jul;78(3):184-187. Doi: 10.1016 / j. maturitas.2014.04.015. Epub 2014 May 1. What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis?

Hensor em, dube b, kingsbury sr, tennant a, conaghan pg., towards a clinical definition of early osteoarthritis: onset of patient-reported knee pain begins on stairs - data from the osteoarthritis initiative. Arthritis care res (hoboken) 29. Doi: 10.1002/acr.22418.

Little p, stuart b, stokes m, nicholls c, roberts l, preece s, cacciatore t, brown s, lewith g, geraghty a, yardley l, o’reilly g, chalk c, sharp d, smith p. Alexander technique and supervised physiotherapy exercises in back pain (aspen): a four-group randomised feasibility trial. Nihr efficacy mech eval 2014;1(2).

Lowe, w., ballinger, c., protheroe, j., lueddeke, j., nutbeam, d., armstrong, r., pearce, j., russell, c.,  mcaffrey, k., adams, j. (2014) suggestions for a research agenda for health literacy and musculoskeletal health – reflections following a qualitative evidence synthesis.  Working papers in health sciences spring 2014 published online

Macfarlane rj, konan s, el-huseinny m and haddad f. A review of outcomes of surgical management of femoroacetabular impingement. Ann r coll surg engl. (2014) jul: 96 (5) 331-8.

Magno e silva mp, winckler c, costa e silva aa, bilzon j, duarte e., sports injuries in paralympic track and field athletes with visual impairment. Med sci sports exerc, 45(5): 908-913. (2013), doi: 10.1249/mss.0b013e31827f06f3.

Matta c, mobasheri a, gergely p , zákány r.  Cell signal. 2014 jul 4. Pii: s0898-6568(14)00208-3. Doi: 10.1016/j.cellsig.2014.06.013. [epub ahead of print] ser/thr-phosphoprotein phosphatases in chondrogenesis: neglected components of a two-player game.

Mcalindon te, bannuru rr, sullivan mc, arden nk, berenbaum f, bierma-zeinstra sm, hawker ga, henrotin y, hunter dj, kawaguchi h, kwoh k, lohmander s, rannou f, roos em and underwood m. Oarsi guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis cartilage mar;22(3):363-88

Mobasheri a, gauthaman k, musumeci g,, chondrocyte and mesenchymal stem cell-based therapies for cartilage. Repair in osteoarthritis and related orthopaedic conditions, maturitas (2014),

Moewis p., boeth h., heller m.o., yntema c., jung t., doyscher r., ehrig r.m., zhong y., taylor w.r.towards understanding knee joint laxity: errors in non-invasive assessment of joint rotation can be eng phys [2014]; 36 (7), 889-95

Morris m, clarke gp, edwards kl, cade je, hulme c. What is the cost of a healthy diet? Using diet data from the uk women's cohort study. Journal of epidemiology & community health (2014) doi:10.1136/jech-2014-204039

Musumeci G, Trovato FM, Loreto C, Leonardi R, Szychlinska MA, Castorina S, Mobasheri A, lubricin expression in human osteoarthritic knee meniscus andsynovial fluid: a morphological, immunohistochemical and biochemical study (2014) acta histochemia

Neogi t, soni a, doherty sa, laslett ll, maciewicz ra, hart dj, zhang w, muir kr, dennison em, wheeler m, cooper c, spector td, cicuttini f, jones g, nevitt m, liu y, arden nk, doherty m, valdes am. Contribution of the comt val158met to symptomatic knee osteoarthritis. Annals of rheumatic diseases (2014), ann rheum dis 2014;73:315-7

Palmer ajr, ayyar-gupta v, dutton sj, rombach i, cooper c, pollard tcb, hollinghurst d, taylor a, barker kl, mcnally eg, beard dj, andrade aj, carr aj, glyn-jones s. Protocol of femoroacetabular impingement trial (fait): a multi-centre randomised controlled trial comparing surgical and non-surgical management of femoroacetabular impingement. Bone joint res 2014 nov;3(11):321-7.

Palmer-green, d and elliott, n.  Sports injury and illness epidemiology: great britain olympic team (teamgb) surveillance during the sochi 2014 winter olympic games.  British journal of sports medicine. (2014) doi:10.1136/bjsports-2014-094206

Ramos y f, metrustry s, arden nk, bay-jensen ac, beekman m, de craen aj, cupples la, esko t, evangelou e, felson dt, hart dj, ioannidis jp, karsdal m, kloppenburg m, lafeber f, metspalu a, panoutsopoulou k, slagboom pe, spector td, van spil ew,uitterlinden ag, zhu y; arcogen consortium; treatoa collaborators, valdes am, van meurs jb, meulenbelt i; arcogen consortium. Meta-analysis identifies lociaffecting levels of the potential osteoarthritis biomarkers scomp and uctx-ii with genome wide significance. J med genet. 2014 sep;51(9):596-604. Doi:10.1136/jmedgenet-2014-102478.

Staunton ca, mobasheri a and barrett-jolley r. High hopes for cannabinoid agonists in the treatment of rheumatic diseases. Bmc musculokeletaldisorders (2014) 15:410 

Taddei f., palmadori i., taylor w.r., heller m.o., bordini b., toni a., schileo e. S.m. Perren award of the esb: safety factor of the proximal femur during gait:a population-based finite element study.j biomech [2014]; 47 (14), 3433-40

Trepczynski a., kutzner i., bergmann g., taylor w.r., heller m.o.  Modulation of the relationship between external knee adduction moments and medial joint contact forces across subjects and activities.arthritis & rheumatology [2014]; 66(5):1218-27

Valdes am, meulenbelt i, chassaing e, arden nk, bierma-zeinstra s, hart d, hofman a, karsdal m, kloppenburg m, kroon hm, slagboom ep, spector td, uitterlinden ag, van meurs jb, bay-jensen ac. Large scale meta-analysis of urinary c-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type ii collagen and their role in prevalence, incidence and progression of osteoarthritis. Osteoarthritis cartilage. 2014 feb 25. Pii: s1063-4584(14)00047-8. Doi: 10.1016/j.joca.2014.02.007. [epub ahead of print] pubmed pmid: 24576742.

Wilkinson dj, franchi mv, brook ms, narici mv, williams jp, mitchell wk, szewczyk nj, greenhaff pl, atherton pj, smith k., a validation of the application of d2o stable isotope tracer techniques for monitoring day-to-day changes in muscle protein sub-fraction synthesis in humans. Am j physiol (2014), 306(5): e571-9

Worsley p, kitsell f, samuel d, stokes m. Validity of measuring distal vastus medialis muscle using rehabilitative ultrasound imaging versus magnetic resonance imaging. Manual therapy. 2014; 19: 259-263.  Doi: 10.1016/j.math.2014.02.002.

Conference Presentations 

Agyapong-Badu S, Samuel D, Warner M, Cooper C, Stokes M. Differences between body mass index and relative thickness of quadriceps muscle and subcutaneous fat as indicators of body composition with healthy ageing. Society for Research & Rehabilitation, 3rd Feb 2014.

Arden, K.M. Leyland, K. Edwards, M.T. Sanchez-Santos, T.D. Spector, A. Nelson, J.M. Jordan, M. Nevitt, D.J. Hunter, N.K. Arden. Racial variation in measures of hip morphology – Oral presentation. C.P.A.

Barnes N, S Agyapong-Badu, B Walsh, M Stokes, D Samuel. Reliability and acceptability of measuring sniff nasal inspiratory pressure (SNIP) and peak inspiratory flow (PIF) to assess respiratory muscle strength in older adults: a preliminary study. Aging Clinical and Experimental Research 2014; 26 (2), 171-176

Botha N, Warner M, Gimpel M, Mottram S, Comerford M, Stokes M. Movement Patterns during a Small Knee Bend Test in Academy Footballers with Femoroacetabular Impingement (FAI).  Working Papers in the Health Sciences 2014; 1:10 Winter ISSN 2051-6266 / 20140056

Darren J. Player, Neil R.W. Martin. Mark P. Lewis, Development of pre-clinical musculoskeletal models to investigate the onset and degeneration of osteoarthritis. Tissue and Cell Engineering Society Annual Meeting, Newcastle, UK, July 2014.

Gates L, Bowen CJ, Arden NK. Defining a multidisciplinary musculoskeletal foot and ankle assessment: results of an international consensus statement. Journal of Foot and Ankle Research Nov 2014. (The Society of Chiropodists and Podiatrists Annual Conference, oral presentation prize: Jewel in the Crown)

Heller, MO. Kinematics of Total Knee Replacements. 3rd Annual Conference of the German Knee Society, 20th -22nd November 2014; Berlin, Germany

Heller, MO. Limitations of musculoskeletal modelling. Orthopaedic Workshop: Towards the next generation of tools for assessing the performance of orthopaedic devices: From concept to the clinic, 7th – 8th May 2014, Flinders University, Adelaide, Australia

Heller, MO. Understanding the spectrum of musculoskeletal loading conditions: key to advancing the frontier in TJR outcome prediction?7th World Congress of Biomechanics, 6th – 11th July 2014, Boston, USA

Jackson K, Newton J, Foster C, Arden N, Judge A, Pinedo-Villanueva, Burrows S, Riddell N and Jones N. A Scoping Project of Current National Service Provision of Exercise Rehabilitation in Multiple Morbidities. BASEM, Edinburgh, October 2014

Jackson K. Predicting Risk of Early Hip Osteoarthritis in Activity-Related Hip Pain; A Delphi Study. Glasgow pre Commonwealth Conference, 2014

Jackson KA, Glyn-Jones S, Batt ME, Arden NK and Newton JL.  Predicting Risk of Early Hip Osteoarthritis in Activity-Related Hip Pain; A Delphi Study. BASEM, Edinburgh, October 2014

Kluzek S. The ARUK Sports, Exercise and osteoarthritis Centre Glasgow pre Commonwealth Conference, 2014

Little P, Stuart B, Stokes M, Nicholls C, Roberts L, Preece S, Cacciatore T, Brown S, Steel C, Lewith G, Geraghty A, Yardley L, O'Reilly G, Chalk C, Sharp D. Alexander Technique and Supervised Physiotherapy Exercises in Back Pain (ASPEN) Feasibility Trial. The Journal of Alternative and Complementary Medicine. May 2014, 20(5): A60-A60.

Palmer-Green. The Injury/Illness Performance Project: Longitudinal surveillance in British Cycling, British Skeleton and British Short Track Speed Skating.  International Olympic Committee Prevention of Injury and Illness is Sport Conference – Monaco, April 2014

Conference Posters

Adams J, Hislop K, Hammond A, Dziedzic K, Gooberman-Hill R, Stokes M, Burridge J, Arden N, Lewis M, Hutt Greenyer C, Barbosa Boucas S (2014). Designing trials of complex occupational therapy with the involvement of patients and clinicians. World Federation of Occupational Therapists Conference, Yokohama, Japan, 18 - 21 Jun 2014

Bartram J, Develin VR.   Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis: Changing research culture and improving understanding of Patient and Public Involvement (PPI). INVOLVE, Birmingham. November 2014

Bowen CJ, Arden NK. Is foot pain considered in the decision to treat knee osteoarthritis with arthroplasty? ESCEO, Seville. April 2014

Culliford DC, Gates L, Gates L, Bowen CJ, McCulloch L, Arden NK. An investigation into the prevalence of disabling foot pain in patients awaiting total knee arthroplasty. Rheumatology 2013. 52 (Supplement 3), iii. British Society for Rheumatology Annual conference, Birmingham, April 2013

Davies M.  A Qualitative Analysis of Current Player Perceptions of Concussion: A Public and Participant Involvement (PPI) Process within Rugby Union. ASEM, Edinburgh, October 2014

Gates L, Bowen CJ, McCulloch L, Arden, NK, Defining a musculoskeletal foot and ankle assessment protocol to be used within the investigation of lower limb osteoarthritis: results of an international consensus statement. ESCEO, Seville. April 2014

Kluzek S, Bay-Jensen A, Spector TD, Hart D, Leyland K, Sanchez-Santos MT, Newton J, Arden NK Higher serum levels of Cartilage Oligomeric Matrix Protein (COMP) are associated with self-reported knee pain. OARSI, Paris. April 2014

Leyland K, Sanchez-Santos MT, Muraki S, Judge A, Spector T, Newton  J, Cooper C, Yoshimura N, Arden N.Manual labour occupations increase the short-term incidence of knee osteoarthritis in Japanese, but not Caucasian subjects.  OARSI, Paris. April 2014

Leyland, K, Sanchez-Santos MT, Kluzek S, Prieto-Alhambra D, Spector T, Hart D, Newton J, Arden NK. OARSI, Paris. April 2014Subjects with self-reported baseline injury have an increased risk of symptomatic radiographic knee osteoarthritis over twenty-years. 

McQueen PL, Bowen CJ, Daniels M, Cherry L, Doherty M, Arden NK. Radiographical abnormality of hallucal sesamoids in middle-aged females. The Society of Chiropodists and Podiatrists Annual Conference. November 2014

McQueen PL, Bowen CJ, Daniels M, Doherty M, Arden NK (2014) Orthoses; the honest problem with patient success when proving the value of a key podiatric treatment. The Society of Chiropodists and Podiatrists Annual Conference. November 2014

Paton, B.  Poster presentation Effort European orthopaedic conference 2014 Istanbul Turkey 

Reports - 2014

Musculoskeletal health – a public health approach  Arthritis Research UK



Hardcastle SA, Dieppe P, Gregson CL, Arden NK, Spector TD, Hart DJ, Edwards MH, Dennison EM, Cooper C, Sayers A, Williams M, Davey Smith G, Tobias JH. Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis.

Collinson M and Mamode L. Arthritis Research UK Centre for Sport, Exercise and OA Internships.  Podiatry Now 2014

Debbie Palmer Green was involved in an article written for Arthritis Care Magazine – Inspire ‘Giving exercise a sporting chance’

Awarded Patents

Heller, MO and Duda, GN (Patent Holders) (2014) Component and method for assembling an implant arrangement. US Patent 8,906,091